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Imagine a doctor prescribing antibiotic ear drops to treat an ear infection. The patient, who does not play sports, painfully ruptures an Achilles tendon a couple of weeks later, perhaps while simply walking across the living room. Few would link those ear drops to the injury. It defies common sense.
In a paper published last month in the journal Clinical Infectious Diseases, University of Florida Health researchers found a more than four-fold heightened risk of an Achilles tendon rupture after use of quinolone ear drops, compared with other antibiotics.

https://ufhealth.org/news/2022/uf-health-researchers-find-quinolone-ear-drops-associated-tendon-ruptures