"One dose of psilocybin induced rapid growth of dendritic spines in the frontal cortex of mice". "Using chronic two-photon microscopy the researchers imaged the synaptic architecture of the medial frontal cortex in a number of mice." "Within 24 hours of a single psychedelic dose the researchers detected increases in dendritic spine size and density." "One month later a small amount of these new neuronal connections were still present."

"Alongside these structural changes the researchers note functional and behavioral changes were also detected in the animals following the single psilocybin dose. Increased excitatory neurotransmission in the frontal cortex was measured in the mice and stress-related behaviors reduced."

Landmark study shows one dose of psilocybin induces new neural connections

#discoveries #neuroscience #psychedelics #psilocybin #neuroplasticity #neurogenisis #depression