Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis
Most industrial medicine lacks high quality scientific support, and a majority of studies on the majority of treatments do not evaluate safety and harms of the interventions that its sponsors are selling.

"In this large sample of 1567 interventions studied within Cochrane reviews, only 5.6% were supported by high quality evidence (...) Harms were measured for 577 (36.8%) interventions."

https://www.jclinepi.com/article/S0895-4356(22)00100-7/fulltext
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